Vulnerable neurons linked to social dysfunction in autistic mice
www.riken.jp
RIKEN researchers have shown in a mouse model of autism that specific oxytocin-secreting neurons in the brain are disproportionately disrupted and that neurostimulation can restore social behaviors.

Initially I was all but I don’t want to be social. Then I was oh that’s what their talking about. I feel I am social enough though. And all science should be repeated for vapidity.

    • OldManBOMBIN@lemmy.world
      0·
      2 months ago

      Check to see if it likes solving mazes without the reward of cheese at the end. Just the satisfaction of being an autistic little mouse in a maze.

    • doo@sh.itjust.worksEnglish
      0·
      2 months ago

      Haven’t you heard about the human autism detectors? Those people who say: “Oh, but you don’t look autistic!”

      /s

        • sp3ctr4l@lemmy.zipEnglish
          0·
          2 months ago

          Hey I mean, I am 99% on the side of ‘/s is way, way too overused’, but, much like with cursing or other kinds of emphasis and tone indicative formatting, there are cases where it makes sense to use, and used sparingly.

          We’re in an autism community.

          This is the most likely place you’re going to get people interpreting possibly sarcastic statements literally, with no verbal intonation to go off of.

          With the statement you are criticizing for using the /s mark… that could very easily just be interpreted by people, especially autistic people, as completely serious, unironic, and not sarcastic…

          …because many people, again, especially autistic people, have heard people say basically exactly that statement entirely seriously and honestly.

          EDIT: Ironically, you being crude and dismissive while tone policing is arguably even more ‘reddit bullshit’ than using /s in an autism community, which almost certainly has more interaction from autistic people, who are well known to take things completely literally more often than others.

            • sp3ctr4l@lemmy.zipEnglish
              0·
              2 months ago

              =D

              EDIT: wow, ok.

              HawtTism appears to be a common troll.

              Account created about 2 months ago, basically every single comment they’ve made recently is massively downvoted or has been deleted by a moderator… or both.

              Thank god lemmy has a block feature.

      • Possibly linux@lemmy.zipEnglish
        0·
        2 months ago

        Rant incoming

        I wish I didn’t seem Autistic. You don’t need to bring r/Autism here.

        I feel like a bunch of people on Reddit aren’t really Autistic. They just think it is cool to be Autistic and they like to think they are better than the rest of humanity. Chances are they have other related things like ADHD. I hate to go around telling people they aren’t Autistic but it is really not cool to idolize Autism. People on Reddit go around saying things like “ableism” when a lot of us struggle to mask effectively. Maybe you are Autistic but if people can’t tell you are in a much better position than some. Autistic people need to work way harder to succeed in life. We should celebrate success in fitting in to society as long as it doesn’t mean a broken work life balance.

    • sp3ctr4l@lemmy.zipEnglish
      0·
      2 months ago

      They used the valproic-acid mouse model of autism spectrum disorder; such mice exhibit reduced social behaviors as a result of being exposed to the anti-epileptic drug valproic acid in the womb.

      Just like with autistic humans, you flood them with valproic acid while they are gestating.

      /s

      https://www.drugs.com/sfx/valproic-acid-side-effects.html

      Valproate can impair cognitive development with prenatal exposure and produce major congenital malformations, particularly neural tube defects (eg, spina bifida), and neurodevelopmental disorders.

      Basically, drug manufacturers decided that autism is the same thing as chemically lobotomizing and physically deforming the subject in utero, because chemically lobotomized mice are less social.

      I wish I was making this up, but I’m not.

      https://pmc.ncbi.nlm.nih.gov/articles/PMC4688329/

      Autism is a specific disorder in humans, and most of its symptoms can only be approximated by animal models.

      VPA induces ASD both in human and animals. The etiological mechanism may involve changes in epigenetic marks, expression level of genetic determinants as well as brain lesion.

      Translated: If we give flood mice with valproic acid in utero, they develop brain lesions, which makes them kind of retarded (they literally use mental retardation as a ‘common symptom’ of autism in the paper) and bad at socializing, therefore that’s basically the same as autism.

      To apply this directly to humans, when an adult autism diagnosis requires something like a year or two of continuous meeting with a PhD psychologist, is completely bonkers.

      Given that the core ‘chemical imbalance’ model that was the theoretical underpinning for the development of SSRIs has been shown to be at best, wildly incorrect, and at worst, totally bunk, I’d say this study is horseshit.

      • setVeryLoud(true);@lemmy.ca
        0·
        2 months ago

        Sounds like this study, and other studies using VPA-induced “ASD” in animal models, are straight up dangerous and could lead to negative consequences for the neurodivergent community due to wrong results.